26 Results for "

Vinca erecta Regel & Schmalh.

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Vinca erecta Regel & Schmalh." in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B1180
CAS No.: 4880-88-0
Synonyms: (-)-Eburnamonine; (-)-Vincamone
Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
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3
3 Cited Publications
Cat. No.: HY-N0252
CAS No.: 2468-21-5
Synonyms: (+)-3,4-Didehydrocoronaridine
Catharanthine ((+)-3,4-Didehydrocoronaridine), a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca 2+ channel (VOCC). Catharanthine has IC50s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine lowers blood pressure (BP), heart rate (HR). Catharanthine has anti-cancer activity .
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3
3 Cited Publications
Cat. No.: HY-N0252A
CAS No.: 4168-17-6
Synonyms: (+)-3,4-Didehydrocoronaridine Tartrate
Catharanthine ((+)-3,4-Didehydrocoronaridine) Tartrate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca 2+ channel (VOCC). Catharanthine Tartrate has IC50s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Tartrate lowers blood pressure (BP), heart rate (HR). Catharanthine Tartrate has anti-cancer activity .
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2
2 Cited Publications
Cat. No.: HY-N0687
CAS No.: 2182-14-1
Vindoline is an orally active vinca alkaloid. Vindoline can be extracted from the leaves of Catharanthus roseus. Vindoline has a weak inhibitory effect on the self-assembly of tubulin. Vindoline alleviates Apoptosis, inhibits p-p65 and p-ERK. Vindoline improves diabetes, bone loss, osteoarthritis, and kidney damage .
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1
1 Cited Publications
Cat. No.: HY-N2453
CAS No.: 508-75-8
Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties .
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1
1 Cited Publications
Cat. No.: HY-N4150
CAS No.: 548-75-4
Synonyms: Quercetagetin-7-O-glucoside
Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta). Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-κB activation. Quercetagitrin is a dual-target inhibitor of PTPN6 (IC50 = 1 μM) and PTPN9 (IC50 = 1.7 μM). Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimer’s disease and type 2 diabetes .
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1
1 Cited Publications
Cat. No.: HY-N11911
CAS No.: 14320-81-1
Synonyms: (-)-Verazine
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases .
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1
1 Cited Publications
Cat. No.: HY-N3619
CAS No.: 142741-24-0
Conophylline is a vinca alkaloid extracted from leaves of a tropical plant Ervatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells. Conophylline suppresses HSC and induces apoptosis .
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Cat. No.: HY-128914
CAS No.: 1943604-24-7
Purity:  99.53%
Research Areas:  

Cancer

Tubulysin is a microtubule destabilizer that binds to the β-tubulin peptide site adjacent to the vinca alkaloid binding site and inhibits tubulin polymerization. Tubulysin induces apoptosis and exhibits antiproliferative activity against a variety of human cancer cells, including multidrug-resistant strains. Tubulysin can be conjugated to antibodies via a disulfide-containing quaternary ammonium linker for ADC synthesis . Tubulysin is applicable to tumor-related research .
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Cat. No.: HY-107242
CAS No.: 124961-61-1
Purity:  99.76%
Raddeanoside R8 is a saponin that can be isolated from fresh rhizoma of Anemone raddeana Regel .
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Cat. No.: HY-N0687R
CAS No.: 2182-14-1
Vindoline (Standard) is an analytical standard of Vindoline (HY-N0687). This product is intended for research and analytical applications. Vindoline is an orally active vinca alkaloid. Vindoline can be extracted from the leaves of Catharanthus roseus. Vindoline has a weak inhibitory effect on the self-assembly of tubulin. Vindoline alleviates Apoptosis, inhibits p-p65 and p-ERK. Vindoline improves diabetes, bone loss, osteoarthritis, and kidney damage .
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Cat. No.: HY-178960
Research Areas:  

Cancer

Tubulin-IN-59 (Compound 8g) is an orally active Tubulin inhibitor. Tubulin-IN-59 exhibits potent anti-proliferative activity against HCT116 colorectal cancer, HeLa cervical cancer, and HepG2 liver cancer cell lines, with its IC₅₀ value ranging from 16 to 35 nM. Tubulin-IN-59 arrests HeLa cells in the G2/M phase and induces cell apoptosis. Tubulin-IN-59 demonstrates significant anti-tumor activity in the HT29 human colon cancer mouse xenograft model. Tubulin-IN-59 can be used for the study of colorectal cancer and cervical cancer .
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Cat. No.: HY-N0252B
CAS No.: 153230-94-5
Synonyms: (+)-3,4-Didehydrocoronaridine Sulfate
Catharanthine ((+)-3,4-Didehydrocoronaridine) Sulfate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca 2+ channel (VOCC). Catharanthine Sulfate has IC50s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Sulfate lowers blood pressure (BP), heart rate (HR). Catharanthine Sulfate has anti-cancer activity .
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Cat. No.: HY-N3790
CAS No.: 53526-67-3
Durantoside I is a natural product, that can be isolated from the stems of Duranta erecta .
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Cat. No.: HY-N0252R
CAS No.: 2468-21-5
Synonyms: (+)-3,4-Didehydrocoronaridine (Standard)
Catharanthine (Standard) is the analytical standard of Catharanthine. This product is intended for research and analytical applications. Catharanthine ((+)-3,4-Didehydrocoronaridine), a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca2+ channel (VOCC). Catharanthine has IC50s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine lowers blood pressure (BP), heart rate (HR). Catharanthine has anti-cancer activity .
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Cat. No.: HY-N12424
CAS No.: 1005340-21-5
Elephanoside D (compound 8) is a steroidal saponin isolated from the stems of Yucca elephantipes Regel.
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Cat. No.: HY-129880
CAS No.: 55383-37-4
Synonyms: Deacetylvinblastine hydrazide; DAVLBH
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Desacetylvinblastine hydrazide (Deacetylvinblastine hydrazide; DAVLBH) is an active component of EC145, a folate-targeted drug conjugate. Desacetylvinblastine hydrazide interferes with the formation of the mitotic spindle, and thus inhibits cell division and leads to cell death. Desacetylvinblastine hydrazide exhibits antitumor activity against folate receptor (FR)-positive tumor .
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Cat. No.: HY-N18739
CAS No.: 90131-43-4
Category:  

Extract

Target:  

Others

Tagetes erecta extract is rich in lutein, which exhibits antioxidant, antiinflammatory, antimutagenicity, and immunomodulatory effects.
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Cat. No.: HY-N2453R
CAS No.: 508-75-8
Convallatoxin (Standard) is the analytical standard of Convallatoxin. This product is intended for research and analytical applications. Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties .
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Cat. No.: HY-N4150R
CAS No.: 548-75-4
Synonyms: Quercetagetin-7-O-glucoside (Standard)
Quercetagitrin (Standard) is the analytical standard of Quercetagitrin. This product is intended for research and analytical applications. Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta). Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-κB activation. Quercetagitrin is a dual-target inhibitor of PTPN6 (IC50 = 1 μM) and PTPN9 (IC50 = 1.7 μM). Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimer’s disease and type 2 diabetes .
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